Saturday, January 3, 2009

IUPAC OF ANTI-HYPERTENSIVE AGENT

Guanethidine:- [2- (hexa hydro- 1 (2 H)- azocinyl )ethyl ]guanidine

Reserpine:- (3 b ,16 b ,17 a ,18 b ,20 a)- 11 ,17- di methoxy- 18- [(3 ,4 ,5- tri methoxy benzoyl )oxy ]yohimban-
16- carboxylic acid methyl ester

Phentolamine:- 3- [[(4 ,5- di hydro- 1 H- imidazol- 2- yl )methyl ](4- methyl phenyl )amino ]phenol

Phenoxybenzamine:- N- (2- chloro ethyl)- N- (1- methyl- 2- phenoxy ethyl )benzene methan amine
Atenolol:- 4- [2- hydroxy- 3- [(1- methyl ethyl )amino ]propoxy ]benzene acet amide

Propranolol:- 1- [(1- methyl ethyl )amino]- 3- (1- naphthalenyl oxy)- 2- propanol

Timolol:- (S)- 1- [(1 ,1- di methyl ethyl )amino]- 3- [[4- (4- morpholinyl)- 1 ,2 ,5- thia di azol- 3- yl ]oxy]- 2-
propanol
Terazosin:- 1- (4- amino- 6 ,7- di ethoxy- 2- quinazolinyl)- 4- [(tetra hydro- 2- furanyl )carbonyl ]piperazine

VerapamilL:- a- [3- [[2- (3 ,4- di methoxy phenyl )ethyl ]methyl amino ]propyl]- 3 ,4- di methoxy- a- (1- methyl
ethyl )benzene aceto nitrile

Nifedipine:- 1 ,4- di hydro- 2 ,6- di methyl- 4- (2- nitro phenyl)- 3 ,5- pyridine di carboxylic acid di methyl ester

Diltiazem:- (2 S- cis)- 3- (acetyl oxy)- 5- [2- (di methyl amino )ethyl]- 2 ,3- di hydro- 2- (4- methoxy phenyl)- 1 ,
5- benzo thiazepin- 4 (5 H)- one

Captopril:- (S)- 1- (3- mercapto- 2- methyl- 1- oxo propyl)- L- proline

Enalapril:- (S)- 1- [N- [1- (ethoxy carbonyl)- 3- phenyl propyl]- L- alanyl]- L- proline
Use: antihypertensive (ACE inhibitor

Lisinopril:- (S)- 1- [N 2- (1- carboxy- 3- phenyl propyl)- L- lysyl]- L- proline
Use: angiotensin-converting enzyme inhibitor (foruse as antihypertensive and in congestive
heart failure, oral absorption about 25 % (6-60%), long acting (plasma half-life 12.6 hrs),once-daily dosing

Losartan potassium:- 2- butyl- 4- chloro- 1- [[2 '-(1 H- tetrazol- 5- yl )[1 ,1 '-bi phenyl]- 4- yl ]methyl]- 1 H- imidazole- 5-methanol mono potassium salt

Use: antihypertensive, angiotensin II blocker
Spironolactone:- (7 a ,17 a)- 7- (acetyl thio)- 17- hydroxy- 3- oxo pregn- 4- ene- 21- carboxylic acid g- lactone
Use: diuretic (aldosterone antagonist

Pargyline:- N- methyl- N- 2- propynyl benzene methan amine
Use: MAO-inhibitor, antihypertensive

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